You’ll still have to adjust doors and jambs to compensate for imperfections in a wall frame.
You’ll select a right or left hand door based on this.
You also need a precise measurement of your rough opening.
This will allow for final door adjustments to get it square by adding shims.
Any gaps around the door will be covered by the door casing.
Check out the video above, from Fine Homebuilding, for complete instructions for installing a prehung door.
Note, the video example uses a plumb and level door opening.
You won’t always be so lucky.
Install a Prehung Exterior Door| Fine Homebuilding